CMap Candidate Details

Structure:
CMap ID: C32572
Pert ID: BRD-K95202259
Compound Name: ML-3163
Targets: MAPK14
MoA: P38 MAPK inhibitor
SMILES: C[S+](O)c1ccc(CSc2nc(c([nH]2)c3ccc(F)cc3)c4ccncc4)cc1
InchiKey: ANMPJJNVRCURIU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1794 BRD-K95202259 HA1E 10 uM 6 h 0.31 1.28 0.61 0.0 0.0 0.0
2017 BRD-K95202259 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2181 BRD-K95202259 PC3 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
2667 BRD-K95202259 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.06
39242 BRD-K95202259 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39380 BRD-K95202259 A549 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
39850 BRD-K95202259 ASC 10 uM 24 h 0.22 0.92 0.04 0.32 1.14 0.85
40138 BRD-K95202259 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
40398 BRD-K95202259 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40545 BRD-K95202259 MCF??7.00 10 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
41271 BRD-K95202259 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41612 BRD-K95202259 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).