CMap Candidate Details

Structure:
CMap ID: C32576
Pert ID: BRD-K95212245
Compound Name: DM-161
Targets: --
MoA: --
SMILES: COc1ccc(COC[C@H](C)N2C[C@@H](C)[C@H](CN(C)S(=O)(=O)c3ccc(F)cc3)OCCCC[C@H](C)Oc3ccc(NC(=O)Nc4ccccc4)cc3C2=O)cc1
InchiKey: NJCFHVZVQQXDMT-FBYVDAEASA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16333 BRD-K95212245 A375 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
16829 BRD-K95212245 A549 10 uM 6 h -0.23 -0.95 0.09 0.0 0.0 0.0
17155 BRD-K95212245 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17494 BRD-K95212245 HEPG2 10 uM 6 h 0.24 1.01 0.12 0.23 0.8 0.08
17840 BRD-K95212245 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
18191 BRD-K95212245 MCF??7.00 10 uM 6 h -0.18 -0.76 0.0 -0.25 -0.84 0.17
18360 BRD-K95212245 PC3 10 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
18875 BRD-K95212245 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).