CMap Candidate Details

Structure:
CMap ID: C32599
Pert ID: BRD-K95309561
Compound Name: dienestrol
Targets: ESR1
MoA: Estrogen receptor agonist
SMILES: CC=C(c1ccc(O)cc1)C(c1ccc(O)cc1)=CC
InchiKey: NFDFQCUYFHCNBW-SCGPFSFSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1364 BRD-K95309561 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
5699 BRD-K95309561 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6348 BRD-K95309561 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41989 BRD-K95309561 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42499 BRD-K95309561 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43674 BRD-K95309561 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43975 BRD-K95309561 PHH 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
44221 BRD-K95309561 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
119417 BRD-K95309561 A375 10 uM 24 h -0.28 -1.17 0.49 0.26 0.92 0.26
119478 BRD-K95309561 HA1E 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119553 BRD-K95309561 HEPG2 0.04 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
119583 BRD-K95309561 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119614 BRD-K95309561 MCF??7.00 0.12 uM 24 h 0.21 0.88 0.02 -0.27 -0.91 0.31
119644 BRD-K95309561 PC3 0.37 uM 24 h 0.27 1.13 0.3 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).