CMap Candidate Details

Structure:
CMap ID: C32640
Pert ID: BRD-K95435023
Compound Name: PHA-665752
Targets: MET
MoA: C-Met inhibitor
SMILES: Cc1[nH]c(C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1
InchiKey: OYONTEXKYJZFHA-SSHUPFPWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4505 BRD-K95435023 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4971 BRD-K95435023 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37201 BRD-K95435023 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37419 BRD-K95435023 A549 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
37766 BRD-K95435023 ASC 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
37961 BRD-K95435023 HEPG2 10 uM 6 h 0.23 0.94 0.06 0.0 0.0 0.0
38799 BRD-K95435023 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39023 BRD-K95435023 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91974 BRD-K95435023 SKBR3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
92014 BRD-K95435023 BT20 10 uM 24 h -0.23 -0.98 0.11 0.35 1.23 1.24
92063 BRD-K95435023 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92132 BRD-K95435023 HS578T 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92186 BRD-K95435023 HT29 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
92230 BRD-K95435023 MCF10A 10 uM 3 h -0.23 -0.96 0.1 0.0 0.0 0.0
92251 BRD-K95435023 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92287 BRD-K95435023 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92335 BRD-K95435023 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).