CMap Candidate Details

Structure:
CMap ID: C32705
Pert ID: BRD-K95609758
Compound Name: BMS-191011
Targets: KCNMA1
MoA: Potassium channel activator
SMILES: Oc1ccc(Cl)cc1Cn1nc(oc1=O)-c1ccc(cc1)C(F)(F)F
InchiKey: QKOWACXSXTXRKA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9010 BRD-K95609758 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9130 BRD-K95609758 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9959 BRD-K95609758 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
10329 BRD-K95609758 HCC515 10 uM 6 h -0.26 -1.1 0.34 0.0 0.0 0.0
10636 BRD-K95609758 HCT116 10 uM 6 h 0.25 1.03 0.13 0.0 0.0 0.0
11045 BRD-K95609758 HT29 10 uM 24 h -0.18 -0.73 0.0 -0.23 -0.78 0.1
11622 BRD-K95609758 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11879 BRD-K95609758 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12177 BRD-K95609758 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12415 BRD-K95609758 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.64
12531 BRD-K95609758 PC3 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
12911 BRD-K95609758 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13057 BRD-K95609758 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13519 BRD-K95609758 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39851 BRD-K95609758 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40139 BRD-K95609758 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40669 BRD-K95609758 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.24
40946 BRD-K95609758 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41272 BRD-K95609758 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41613 BRD-K95609758 SKB 10 uM 24 h -0.2 -0.84 0.01 0.25 0.88 0.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).