CMap Candidate Details

Structure:
CMap ID: C32760
Pert ID: BRD-K95785537
Compound Name: PP-2
Targets: LCK; SRC
MoA: Src inhibitor
SMILES: CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc12
InchiKey: PBBRWFOVCUAONR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2950 BRD-K95785537 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
3298 BRD-K95785537 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3571 BRD-K95785537 PC3 10 uM 24 h 0.21 0.89 0.02 0.24 0.86 0.16
3904 BRD-K95785537 VCAP 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
41857 BRD-K95785537 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42159 BRD-K95785537 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42500 BRD-K95785537 ASC 10 uM 24 h -0.32 -1.32 0.84 0.0 0.0 0.0
42809 BRD-K95785537 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.43
43096 BRD-K95785537 HT29 10 uM 6 h -0.25 -1.03 0.2 0.0 0.0 0.0
43365 BRD-K95785537 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43976 BRD-K95785537 PHH 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.03
44222 BRD-K95785537 SKB 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.65
99110 BRD-K95785537 NEU 10 uM 6 h -0.24 -1.0 0.15 -0.29 -0.97 0.45
99260 BRD-K95785537 NPC 10 uM 6 h -0.22 -0.91 0.05 0.32 1.13 0.82
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).