CMap Candidate Details

Structure:
CMap ID: C03280
Pert ID: BRD-K02708799
Compound Name: GSK-1059615
Targets: --
MoA: --
SMILES: O=C1NC(=O)C(S1)=C/c1ccc2nccc(-c3ccncc3)c2c1
InchiKey: QDITZBLZQQZVEE-MHWRWJLKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92059 BRD-K02708799 HA1E 1.11 uM 24 h 0.0 0.0 0.0 -0.17 -0.59 0.0
92128 BRD-K02708799 HS578T 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92181 BRD-K02708799 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92271 BRD-K02708799 MCF??7.00 1.11 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92305 BRD-K02708799 MDAMB231 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92359 BRD-K02708799 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92452 BRD-K02708799 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92554 BRD-K02708799 HME1 10 uM 3 h 0.0 0.0 0.0 0.35 1.24 1.24
92692 BRD-K02708799 LNCAP 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92722 BRD-K02708799 MCF10A 0.12 uM 3 h 0.24 1.02 0.13 0.24 0.85 0.15
93005 BRD-K02708799 CD34 3.33 uM 24 h 0.0 0.0 0.0 -0.41 -1.37 2.02
93092 BRD-K02708799 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93133 BRD-K02708799 HELA 3.33 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
93231 BRD-K02708799 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93284 BRD-K02708799 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93423 BRD-K02708799 NPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93549 BRD-K02708799 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
93589 BRD-K02708799 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93799 BRD-K02708799 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93933 BRD-K02708799 HEPG2 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94112 BRD-K02708799 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94246 BRD-K02708799 SHSY5Y 3.33 uM 24 h 0.28 1.16 0.35 0.0 0.0 0.0
94419 BRD-K02708799 A375 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94452 BRD-K02708799 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94490 BRD-K02708799 ASC 0.04 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
95122 BRD-K02708799 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95238 BRD-K02708799 SKL 0.12 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).