CMap Candidate Details

Structure:
CMap ID: C03282
Pert ID: BRD-K02715688
Compound Name: hydrastine
Targets: --
MoA: --
SMILES: COc1ccc2[C@H](OC(=O)c2c1OC)[C@@H]1N(C)CCc2cc3OCOc3cc12
InchiKey: JZUTXVTYJDCMDU-MOPGFXCFSA-N
Compound Aliases: hydrastine-(1r,-9s)

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4040 BRD-K02715688 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
4339 BRD-K02715688 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4875 BRD-K02715688 VCAP 10 uM 24 h 0.26 1.1 0.24 0.33 1.18 0.97
37115 BRD-K02715688 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37360 BRD-K02715688 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37579 BRD-K02715688 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37866 BRD-K02715688 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38045 BRD-K02715688 HT29 10 uM 6 h -0.22 -0.91 0.05 0.26 0.92 0.25
38176 BRD-K02715688 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38416 BRD-K02715688 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38680 BRD-K02715688 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38905 BRD-K02715688 SKB 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
97186 BRD-K02715688 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).