CMap Candidate Details

Structure:
CMap ID: C32854
Pert ID: BRD-K96037667
Compound Name: norethindrone
Targets: PGR
MoA: Progestogen hormone; Progesterone receptor agonist
SMILES: CC(=O)O[C@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C)C#C
InchiKey: IMONTRJLAWHYGT-ZCPXKWAGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49919 BRD-K96037667 A375 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.49
50269 BRD-K96037667 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50439 BRD-K96037667 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50618 BRD-K96037667 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50794 BRD-K96037667 MCF??7.00 10 uM 6 h 0.28 1.16 0.35 -0.24 -0.82 0.15
50966 BRD-K96037667 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51082 BRD-K96037667 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52755 BRD-K96037667 HEPG2 20 uM 24 h -0.21 -0.85 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).