CMap Candidate Details

Structure:
CMap ID: C32876
Pert ID: BRD-K96084870
Compound Name: DMBI
Targets: PDGFRB
MoA: PDGFR inhibitor; VEGFR inhibitor
SMILES: CN(C)c1ccc(/C=C2/C(=O)Nc3ccccc23)cc1
InchiKey: UAKWLVYMKBWHMX-RVDMUPIBSA-N
Compound Aliases: dmbi

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5377 BRD-K96084870 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5700 BRD-K96084870 HCC515 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
6225 BRD-K96084870 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6605 BRD-K96084870 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44463 BRD-K96084870 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44736 BRD-K96084870 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45055 BRD-K96084870 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45340 BRD-K96084870 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
45600 BRD-K96084870 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45727 BRD-K96084870 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46164 BRD-K96084870 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46479 BRD-K96084870 PHH 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
46808 BRD-K96084870 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).