CMap Candidate Details

Structure:
CMap ID: C32947
Pert ID: BRD-K96319534
Compound Name: phentermine
Targets: SLC6A2
MoA: Dopamine uptake inhibitor; Serotonin reuptake inhibitor
SMILES: CC(C)(N)Cc1ccccc1
InchiKey: DHHVAGZRUROJKS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5703 BRD-K96319534 HCC515 10 uM 24 h -0.3 -1.25 0.71 -0.3 -1.01 0.56
6408 BRD-K96319534 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
37770 BRD-K96319534 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37965 BRD-K96319534 HEPG2 10 uM 6 h 0.22 0.91 0.03 -0.26 -0.86 0.22
38581 BRD-K96319534 NPC 10 uM 24 h 0.24 0.99 0.1 0.29 1.03 0.52
96471 BRD-K96319534 A375 1.11 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
96537 BRD-K96319534 PC3 1.11 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
128136 BRD-K96319534 A549 0.125 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
128217 BRD-K96319534 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
128296 BRD-K96319534 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128350 BRD-K96319534 THP1 0.04 uM 24 h 0.24 1.02 0.12 0.23 0.8 0.08
135806 BRD-K96319534 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135847 BRD-K96319534 HEK293 0.01 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
135891 BRD-K96319534 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
135937 BRD-K96319534 HT29 0.25 uM 24 h 0.25 1.04 0.15 0.0 0.0 0.0
135980 BRD-K96319534 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136026 BRD-K96319534 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136126 BRD-K96319534 YAPC 0.03 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).