CMap Candidate Details

Structure:
CMap ID: C32953
Pert ID: BRD-K96342952
Compound Name: tobramycin
Targets: --
MoA: --
SMILES: NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@@H]3O)[C@@H]2O)[C@@H](N)C[C@@H]1O
InchiKey: NLVFBUXFDBBNBW-RJHRXKMUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128109 BRD-K96342952 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128138 BRD-K96342952 A549 0.125 uM 24 h -0.24 -0.98 0.12 0.28 1.0 0.43
128220 BRD-K96342952 MCF10A 0.04 uM 24 h -0.29 -1.21 0.58 0.0 0.0 0.0
128259 BRD-K96342952 MCF??7.00 1.11 uM 24 h -0.26 -1.08 0.31 0.33 1.16 0.91
128299 BRD-K96342952 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128353 BRD-K96342952 THP1 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
135809 BRD-K96342952 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.78
135849 BRD-K96342952 HEK293 2.22 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
135894 BRD-K96342952 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135940 BRD-K96342952 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135983 BRD-K96342952 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136058 BRD-K96342952 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
136129 BRD-K96342952 YAPC 0.03 uM 24 h 0.28 1.18 0.4 0.3 1.05 0.57
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).