CMap Candidate Details

Structure:
CMap ID: C32961
Pert ID: BRD-K96354014
Compound Name: nifedipine
Targets: CACNA1C; CACNA1D; CACNA1F; CACNA1S; CACNA2D1
MoA: Calcium channel blocker
SMILES: COC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC
InchiKey: HYIMSNHJOBLJNT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9011 BRD-K96354014 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9131 BRD-K96354014 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9554 BRD-K96354014 AGS 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.64
9862 BRD-K96354014 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10099 BRD-K96354014 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10331 BRD-K96354014 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10637 BRD-K96354014 HCT116 10 uM 6 h -0.24 -0.98 0.12 0.23 0.83 0.11
11310 BRD-K96354014 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.21 0.76 0.05
11623 BRD-K96354014 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11880 BRD-K96354014 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12416 BRD-K96354014 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13059 BRD-K96354014 THP1 10 uM 6 h 0.23 0.95 0.06 0.27 0.95 0.32
13403 BRD-K96354014 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13712 BRD-K96354014 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45056 BRD-K96354014 ASC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
46165 BRD-K96354014 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46809 BRD-K96354014 SKB 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.36 2.02
52875 BRD-K96354014 HEPG2 40 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53090 BRD-K96354014 MCF10A 100 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
91033 BRD-K96354014 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96024 BRD-K96354014 PHH 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117537 BRD-K96354014 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117618 BRD-K96354014 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).