CMap Candidate Details

Structure:
CMap ID: C00331
Pert ID: BRD-A13122391
Compound Name: triptolide
Targets: --
MoA: --
SMILES: CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5CC6C7=C(CC[C@@]64C)C(=O)OC7)[C@@H]1O
InchiKey: DFBIRQPKNDILPW-KTGKZQHOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9050 BRD-A13122391 A375 0.08 uM 6 h -0.23 -0.95 0.09 0.34 1.21 1.15
9269 BRD-A13122391 AGS 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9572 BRD-A13122391 H1299 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9963 BRD-A13122391 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10333 BRD-A13122391 HCC515 0.08 uM 6 h 0.0 0.0 0.0 0.42 1.48 2.25
10651 BRD-A13122391 HEPG2 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10894 BRD-A13122391 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11322 BRD-A13122391 NCIH2073 0.08 uM 6 h -0.18 -0.76 0.0 0.23 0.81 0.09
11640 BRD-A13122391 NCIH508 0.08 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.91
11892 BRD-A13122391 NCIH596 0.08 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.17
12189 BRD-A13122391 NOMO1 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12574 BRD-A13122391 PC3 0.08 uM 6 h 0.0 0.0 0.0 0.4 1.42 2.19
12648 BRD-A13122391 SW480 0.08 uM 6 h 0.0 0.0 0.0 0.36 1.26 1.29
13063 BRD-A13122391 THP1 0.08 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.43
13130 BRD-A13122391 U937 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13524 BRD-A13122391 VCAP 0.08 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.32
90536 BRD-A13122391 A549 0.04 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90544 BRD-A13122391 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).