CMap Candidate Details

Structure:
CMap ID: C33104
Pert ID: BRD-K96778649
Compound Name: tyrphostin-47
Targets: EGFR
MoA: EGFR inhibitor
SMILES: NC(=S)/C(=C/c1ccc(O)c(O)c1)/C#N
InchiKey: ZGHQGWOETPXKLY-XVNBXDOJSA-N
Compound Aliases: TYRPHOSTIN-47

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3078 BRD-K96778649 HA1E 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.23
3414 BRD-K96778649 HCC515 10 uM 6 h 0.0 0.0 0.0 0.28 1.01 0.44
3574 BRD-K96778649 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3908 BRD-K96778649 VCAP 10 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
41858 BRD-K96778649 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41991 BRD-K96778649 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42502 BRD-K96778649 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42811 BRD-K96778649 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43098 BRD-K96778649 HT29 10 uM 6 h -0.22 -0.93 0.07 0.0 0.0 0.0
43247 BRD-K96778649 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
43676 BRD-K96778649 NPC 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.39
43977 BRD-K96778649 PHH 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.28
44224 BRD-K96778649 SKB 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).