CMap Candidate Details

Structure:
CMap ID: C33112
Pert ID: BRD-K96799727
Compound Name: pifithrin-mu
Targets: HSPA1A; TP53
MoA: HSP inhibitor
SMILES: NS(=O)(=O)C#Cc1ccccc1
InchiKey: ZZUZYEMRHCMVTB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5481 BRD-K96799727 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6306 BRD-K96799727 PC3 10 uM 6 h -0.23 -0.96 0.1 0.26 0.93 0.26
6394 BRD-K96799727 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9256 BRD-K96799727 A549 10 uM 6 h -0.25 -1.02 0.18 0.0 0.0 0.0
9555 BRD-K96799727 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9863 BRD-K96799727 H1299 10 uM 6 h -0.19 -0.81 0.0 0.0 0.0 0.0
10279 BRD-K96799727 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10638 BRD-K96799727 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10886 BRD-K96799727 HEPG2 10 uM 6 h 0.27 1.12 0.26 0.0 0.0 0.0
11069 BRD-K96799727 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11624 BRD-K96799727 NCIH2073 10 uM 6 h 0.28 1.19 0.41 0.0 0.0 0.0
11881 BRD-K96799727 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12178 BRD-K96799727 NCIH596 10 uM 6 h 0.3 1.24 0.51 0.0 0.0 0.0
12912 BRD-K96799727 SW480 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.29 1.53
12979 BRD-K96799727 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13404 BRD-K96799727 U937 10 uM 6 h -0.23 -0.94 0.08 0.22 0.78 0.06
44464 BRD-K96799727 A375 10 uM 6 h -0.24 -1.0 0.14 0.0 0.0 0.0
46480 BRD-K96799727 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46810 BRD-K96799727 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97682 BRD-K96799727 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98506 BRD-K96799727 NEU 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.22 1.25
98724 BRD-K96799727 NPC 10 uM 6 h 0.0 0.0 0.0 -0.5 -1.68 15.65
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).