CMap Candidate Details

Structure:
CMap ID: C33169
Pert ID: BRD-K97056771
Compound Name: GNF-2
Targets: ABL1; BCR
MoA: Abl kinase inhibitor
SMILES: NC(=O)c1cccc(c1)-c1cc(Nc2ccc(OC(F)(F)F)cc2)ncn1
InchiKey: WEVYNIUIFUYDGI-UHFFFAOYSA-N
Compound Aliases: HY-11007

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
30598 BRD-K97056771 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30882 BRD-K97056771 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
31489 BRD-K97056771 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.78
33185 BRD-K97056771 SKB 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
33521 BRD-K97056771 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91527 BRD-K97056771 BT20 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91592 BRD-K97056771 HS578T 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91671 BRD-K97056771 MCF??7.00 10 uM 24 h 0.28 1.17 0.36 -0.25 -0.86 0.21
91722 BRD-K97056771 MDAMB231 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91784 BRD-K97056771 SKBR3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
94405 BRD-K97056771 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94436 BRD-K97056771 A549 10 uM 24 h -0.25 -1.04 0.21 0.29 1.01 0.45
94531 BRD-K97056771 CD34 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94584 BRD-K97056771 HCC515 1.11 uM 24 h -0.33 -1.37 1.08 0.0 0.0 0.0
94625 BRD-K97056771 HEK293 10 uM 24 h -0.26 -1.06 0.26 0.0 0.0 0.0
94675 BRD-K97056771 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94724 BRD-K97056771 HME1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94779 BRD-K97056771 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94820 BRD-K97056771 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
94872 BRD-K97056771 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 -0.18 -0.59 0.0
94923 BRD-K97056771 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94999 BRD-K97056771 NEU 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95047 BRD-K97056771 NPC 10 uM 24 h 0.24 1.01 0.12 0.34 1.22 1.15
95106 BRD-K97056771 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95144 BRD-K97056771 SHSY5Y 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95228 BRD-K97056771 SKL 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
95257 BRD-K97056771 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).