CMap Candidate Details

Structure:
CMap ID: C33195
Pert ID: BRD-K97158071
Compound Name: droperidol
Targets: DRD2
MoA: Dopamine receptor antagonist
SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC(=CC1)n1c2ccccc2[nH]c1=O
InchiKey: RMEDXOLNCUSCGS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5704 BRD-K97158071 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5965 BRD-K97158071 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25456 BRD-K97158071 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39866 BRD-K97158071 ASC 10 uM 24 h 0.22 0.9 0.03 0.0 0.0 0.0
40960 BRD-K97158071 NEU 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
41285 BRD-K97158071 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41628 BRD-K97158071 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128227 BRD-K97158071 MCF10A 0.04 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
128306 BRD-K97158071 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
128334 BRD-K97158071 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135760 BRD-K97158071 A375 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
135777 BRD-K97158071 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135814 BRD-K97158071 HA1E 0.74 uM 24 h -0.21 -0.87 0.02 -0.28 -0.93 0.35
135853 BRD-K97158071 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135901 BRD-K97158071 HELA 0.01 uM 24 h -0.28 -1.17 0.48 0.0 0.0 0.0
135946 BRD-K97158071 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
135990 BRD-K97158071 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
136031 BRD-K97158071 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136091 BRD-K97158071 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136136 BRD-K97158071 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).