CMap Candidate Details

Structure:
CMap ID: C33241
Pert ID: BRD-K97309399
Compound Name: thiothixene
Targets: HTR2A
MoA: Dopamine receptor antagonist
SMILES: CN(C)S(=O)(=O)c1ccc2Sc3ccccc3C(=C/CCN3CCN(C)CC3)c2c1
InchiKey: GFBKORZTTCHDGY-UFWORHAWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4149 BRD-K97309399 HA1E 10 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
4507 BRD-K97309399 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4973 BRD-K97309399 VCAP 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
37771 BRD-K97309399 ASC 10 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
37966 BRD-K97309399 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38582 BRD-K97309399 NPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
39026 BRD-K97309399 SKB 10 uM 24 h 0.26 1.07 0.19 0.0 0.0 0.0
128113 BRD-K97309399 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128144 BRD-K97309399 A549 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
128189 BRD-K97309399 HT29 10 uM 24 h 0.17 0.71 0.0 -0.24 -0.82 0.14
128232 BRD-K97309399 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
128264 BRD-K97309399 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128311 BRD-K97309399 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135857 BRD-K97309399 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135906 BRD-K97309399 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
135995 BRD-K97309399 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
136064 BRD-K97309399 PC3 0.03 uM 24 h 0.2 0.81 0.0 0.0 0.0 0.0
136095 BRD-K97309399 THP1 0.01 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
136141 BRD-K97309399 YAPC 2.22 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).