CMap Candidate Details

Structure:
CMap ID: C03325
Pert ID: BRD-K02867583
Compound Name: minaprine
Targets: HTR2B; SLC6A4
MoA: Serotonin reuptake inhibitor
SMILES: Cc1cc(nnc1NCCN1CCOCC1)-c1ccccc1
InchiKey: LDMWSLGGVTVJPG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6717 BRD-K02867583 A375 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
8641 BRD-K02867583 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122905 BRD-K02867583 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
122981 BRD-K02867583 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123030 BRD-K02867583 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123077 BRD-K02867583 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
123120 BRD-K02867583 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123150 BRD-K02867583 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123192 BRD-K02867583 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131252 BRD-K02867583 A549 0.25 uM 24 h 0.22 0.91 0.03 0.0 0.0 0.0
131285 BRD-K02867583 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131311 BRD-K02867583 HELA 0.03 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
131368 BRD-K02867583 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131406 BRD-K02867583 MCF10A 0.08 uM 24 h -0.22 -0.91 0.06 0.21 0.74 0.04
131505 BRD-K02867583 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).