CMap Candidate Details

Structure:
CMap ID: C33288
Pert ID: BRD-K97440753
Compound Name: BRD-K97440753
Targets: --
MoA: --
SMILES: CC(C)[C@@]1(NC(=O)[C@@H]2C[C@H]3[C@@H](Cc4c[nH]c5cccc3c45)N(C)C2)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](Cc3ccccc3)N2C1=O
InchiKey: DEQITUUQPICUMR-HJPBWRTMSA-N
Compound Aliases: dihydroergocristine

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3305 BRD-K97440753 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3912 BRD-K97440753 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39868 BRD-K97440753 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40153 BRD-K97440753 HEPG2 10 uM 6 h -0.25 -1.05 0.22 0.0 0.0 0.0
40962 BRD-K97440753 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41287 BRD-K97440753 NPC 10 uM 24 h 0.26 1.08 0.22 -0.26 -0.87 0.22
41631 BRD-K97440753 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91333 BRD-K97440753 HUH7 6.66 uM 72 h 0.18 0.75 0.0 -0.3 -1.01 0.56
128402 BRD-K97440753 A549 0.125 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
128462 BRD-K97440753 HEK293 10 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
128487 BRD-K97440753 HELA 10 uM 24 h -0.29 -1.19 0.53 -0.37 -1.24 1.35
128572 BRD-K97440753 JURKAT 3.33 uM 24 h -0.25 -1.06 0.25 0.0 0.0 0.0
128615 BRD-K97440753 MCF??7.00 0.04 uM 24 h -0.28 -1.18 0.51 0.0 0.0 0.0
128664 BRD-K97440753 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128743 BRD-K97440753 THP1 10 uM 24 h -0.34 -1.41 1.21 0.0 0.0 0.0
128782 BRD-K97440753 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136200 BRD-K97440753 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136245 BRD-K97440753 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
136300 BRD-K97440753 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
136322 BRD-K97440753 MCF10A 0.03 uM 24 h 0.3 1.23 0.51 0.0 0.0 0.0
136374 BRD-K97440753 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).