CMap Candidate Details

Structure:
CMap ID: C33313
Pert ID: BRD-K97509413
Compound Name: coumestrol
Targets: ESR1; ESR2
MoA: Estrogen receptor agonist
SMILES: Oc1ccc2c(c1)oc3c2c(=O)oc4cc(O)ccc34
InchiKey: ZZIALNLLNHEQPJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3080 BRD-K97509413 HA1E 10 uM 6 h -0.25 -1.04 0.22 0.0 0.0 0.0
3417 BRD-K97509413 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3657 BRD-K97509413 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3913 BRD-K97509413 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.09
39253 BRD-K97509413 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39386 BRD-K97509413 A549 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
39869 BRD-K97509413 ASC 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
40154 BRD-K97509413 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40412 BRD-K97509413 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.96 0.43
40554 BRD-K97509413 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
40963 BRD-K97509413 NEU 10 uM 24 h -0.26 -1.07 0.28 -0.21 -0.72 0.04
41288 BRD-K97509413 NPC 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
41632 BRD-K97509413 SKB 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).