CMap Candidate Details

Structure:
CMap ID: C33327
Pert ID: BRD-K97564742
Compound Name: mepyramine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: COc1ccc(cc1)CN(CCN(C)C)c1ccccn1
InchiKey: YECBIJXISLIIDS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4264 BRD-K97564742 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4601 BRD-K97564742 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4974 BRD-K97564742 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37203 BRD-K97564742 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37772 BRD-K97564742 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38583 BRD-K97564742 NPC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
39027 BRD-K97564742 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52941 BRD-K97564742 HEPG2 40 uM 24 h -0.24 -1.0 0.15 0.23 0.81 0.09
91135 BRD-K97564742 HUH7 12 uM 72 h 0.0 0.0 0.0 -0.33 -1.1 0.88
128170 BRD-K97564742 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.43
128225 BRD-K97564742 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128261 BRD-K97564742 MCF??7.00 0.37 uM 24 h -0.27 -1.13 0.41 0.35 1.26 1.29
128304 BRD-K97564742 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128333 BRD-K97564742 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135776 BRD-K97564742 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135899 BRD-K97564742 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
135944 BRD-K97564742 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.55
135988 BRD-K97564742 JURKAT 2.22 uM 24 h -0.28 -1.18 0.51 -0.33 -1.1 0.86
136089 BRD-K97564742 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
136134 BRD-K97564742 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).