CMap Candidate Details

Structure:
CMap ID: C33387
Pert ID: BRD-K97746869
Compound Name: chlorpropamide
Targets: ABCC8
MoA: ATP channel blocker
SMILES: CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InchiKey: RKWGIWYCVPQPMF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52992 BRD-K97746869 HEPG2 40 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
96293 BRD-K97746869 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127380 BRD-K97746869 A549 1.11 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
127408 BRD-K97746869 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127483 BRD-K97746869 HT29 10 uM 24 h 0.31 1.29 0.67 0.0 0.0 0.0
127495 BRD-K97746869 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
127589 BRD-K97746869 PC3 10 uM 24 h 0.3 1.23 0.5 0.0 0.0 0.0
127665 BRD-K97746869 YAPC 10 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
135357 BRD-K97746869 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135427 BRD-K97746869 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135461 BRD-K97746869 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
135490 BRD-K97746869 THP1 0.01 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).