CMap Candidate Details

Structure:
CMap ID: C03346
Pert ID: BRD-K02943813
Compound Name: dasabuvir
Targets: --
MoA: --
SMILES: COc1c(cc(cc1C(C)(C)C)-n1ccc(=O)[nH]c1=O)-c1ccc2cc(NS(C)(=O)=O)ccc2c1
InchiKey: NBRBXGKOEOGLOI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122850 BRD-K02943813 A549 10 uM 24 h -0.24 -1.02 0.17 -0.28 -0.95 0.4
122865 BRD-K02943813 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122910 BRD-K02943813 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122948 BRD-K02943813 HELA 10 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
122984 BRD-K02943813 HT29 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.05
123035 BRD-K02943813 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
123079 BRD-K02943813 MCF??7.00 10 uM 24 h 0.25 1.05 0.16 0.0 0.0 0.0
123125 BRD-K02943813 MDAMB231 3.33 uM 24 h 0.26 1.08 0.21 0.0 0.0 0.0
123152 BRD-K02943813 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123197 BRD-K02943813 THP1 10 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
123218 BRD-K02943813 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131218 BRD-K02943813 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131373 BRD-K02943813 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.36
131410 BRD-K02943813 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).