CMap Candidate Details
Structure:
| CMap ID: | C33563 |
| Pert ID: | BRD-K98333955 |
| Compound Name: | NVP-AEW541 |
| Targets: | IGF1R |
| MoA: | IGF-1 inhibitor |
| SMILES: | Nc1ncnc2n(cc(-c3ccc(OCc4ccccc4)cc3)c12)[C@H]1C[C@H](CN2CCC2)C1 |
| InchiKey: | MJEHBQIPZHTMNZ-AQYVVDRMSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 91835 | BRD-K98333955 | HS578T | 0.37 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 91854 | BRD-K98333955 | MCF10A | 0.37 uM | 24 h | -0.18 | -0.77 | 0.0 | -0.3 | -1.01 | 0.57 |
| 91862 | BRD-K98333955 | MCF??7.00 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.39 |
| 91921 | BRD-K98333955 | MDAMB231 | 2.22 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |
| 91975 | BRD-K98333955 | SKBR3 | 2.22 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.33 | -1.12 | 0.97 |