CMap Candidate Details

Structure:
CMap ID: C33581
Pert ID: BRD-K98404142
Compound Name: BRD-K98404142
Targets: G6PD
MoA: Glucose 6-phosphate dehydrogenase inhibitor
SMILES: C[C@@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]2C[C@H](Br)C1=O
InchiKey: CWVMWSZEMZOUPC-RWUIUEHLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9012 BRD-K98404142 A375 12 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.04
9864 BRD-K98404142 H1299 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9962 BRD-K98404142 HA1E 12 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
11625 BRD-K98404142 NCIH2073 12 uM 6 h 0.0 0.0 0.0 -0.33 -1.13 0.97
11882 BRD-K98404142 NCIH508 12 uM 6 h 0.21 0.86 0.01 -0.29 -0.96 0.44
12179 BRD-K98404142 NCIH596 12 uM 6 h 0.18 0.77 0.0 -0.27 -0.9 0.28
12417 BRD-K98404142 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12533 BRD-K98404142 PC3 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12913 BRD-K98404142 SW480 12 uM 6 h 0.0 0.0 0.0 0.34 1.22 1.15
13061 BRD-K98404142 THP1 12 uM 6 h -0.28 -1.16 0.48 0.0 0.0 0.0
13520 BRD-K98404142 VCAP 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118080 BRD-K98404142 A549 12 uM 24 h -0.31 -1.29 0.77 0.0 0.0 0.0
118165 BRD-K98404142 HCC515 0.05 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118215 BRD-K98404142 HEPG2 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118261 BRD-K98404142 HT29 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118302 BRD-K98404142 MCF??7.00 12 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).