CMap Candidate Details

Structure:
CMap ID: C33586
Pert ID: BRD-K98426715
Compound Name: tubacin
Targets: HDAC6
MoA: HDAC inhibitor
SMILES: OCc1ccc(cc1)[C@@H]2C[C@H](CSc3nc(c(o3)c4ccccc4)c5ccccc5)O[C@@H](O2)c6ccc(NC(=O)CCCCCCC(=O)NO)cc6
InchiKey: BHUZLJOUHMBZQY-YXQOSMAKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
47133 BRD-K98426715 A375 10 uM 6 h -0.25 -1.03 0.19 -0.24 -0.79 0.11
47401 BRD-K98426715 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
47794 BRD-K98426715 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48117 BRD-K98426715 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.92 0.32
48443 BRD-K98426715 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48770 BRD-K98426715 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48920 BRD-K98426715 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49149 BRD-K98426715 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49594 BRD-K98426715 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).