CMap Candidate Details

Structure:
CMap ID: C33606
Pert ID: BRD-K98490050
Compound Name: amsacrine
Targets: TOP2A
MoA: Topoisomerase inhibitor
SMILES: COc1cc(NS(=O)(=O)C)ccc1Cc2c3ccccc3nc4ccccc24
InchiKey: JRNUZHHDXNSOMO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5482 BRD-K98490050 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5810 BRD-K98490050 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.54 -1.81 15.65
5966 BRD-K98490050 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6115 BRD-K98490050 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6307 BRD-K98490050 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6607 BRD-K98490050 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.15 1.08
37205 BRD-K98490050 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37318 BRD-K98490050 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37774 BRD-K98490050 ASC 10 uM 24 h 0.27 1.14 0.32 -0.32 -1.07 0.77
38119 BRD-K98490050 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38585 BRD-K98490050 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39028 BRD-K98490050 SKB 10 uM 24 h 0.27 1.12 0.27 0.31 1.08 0.66
96045 BRD-K98490050 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).