CMap Candidate Details

Structure:
CMap ID: C33630
Pert ID: BRD-K98572433
Compound Name: AZD-8931
Targets: --
MoA: --
SMILES: CNC(=O)CN1CCC(CC1)Oc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC
InchiKey: DFJSJLGUIXFDJP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128118 BRD-K98572433 A375 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.41
128148 BRD-K98572433 A549 10 uM 24 h 0.24 0.98 0.09 0.27 0.95 0.31
128173 BRD-K98572433 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128191 BRD-K98572433 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128237 BRD-K98572433 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
128267 BRD-K98572433 MCF??7.00 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
128316 BRD-K98572433 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128338 BRD-K98572433 PC3 10 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
128360 BRD-K98572433 THP1 1.11 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.91
135821 BRD-K98572433 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
135910 BRD-K98572433 HELA 0.74 uM 24 h 0.17 0.7 0.0 0.0 0.0 0.0
136000 BRD-K98572433 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
136146 BRD-K98572433 YAPC 2.22 uM 24 h -0.2 -0.82 0.0 -0.27 -0.91 0.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).