CMap Candidate Details

Structure:
CMap ID: C33645
Pert ID: BRD-K98624455
Compound Name: bepotastine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: OC(=O)CCCN1CCC(CC1)O[C@@H](c1ccc(Cl)cc1)c1ccccn1
InchiKey: YWGDOWXRIALTES-NRFANRHFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
127339 BRD-K98624455 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
127413 BRD-K98624455 HA1E 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
127485 BRD-K98624455 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127500 BRD-K98624455 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127568 BRD-K98624455 MCF??7.00 3.33 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
127594 BRD-K98624455 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127670 BRD-K98624455 YAPC 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
135341 BRD-K98624455 A549 0.08 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
135361 BRD-K98624455 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
135430 BRD-K98624455 MCF10A 2.22 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
135492 BRD-K98624455 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).