CMap Candidate Details

Structure:
CMap ID: C33661
Pert ID: BRD-K98684188
Compound Name: GSK-0660
Targets: PPARD
MoA: PPAR receptor antagonist
SMILES: COC(=O)c1sccc1S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1OC
InchiKey: NDFKBGWLUHKMFY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33735 BRD-K98684188 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33861 BRD-K98684188 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
34219 BRD-K98684188 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34453 BRD-K98684188 HA1E 10 uM 6 h 0.26 1.08 0.2 0.0 0.0 0.0
34721 BRD-K98684188 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35000 BRD-K98684188 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35234 BRD-K98684188 HT29 10 uM 6 h -0.21 -0.87 0.02 -0.32 -1.07 0.76
35499 BRD-K98684188 MCF??7.00 10 uM 6 h 0.21 0.88 0.02 0.0 0.0 0.0
35874 BRD-K98684188 NPC 10 uM 24 h 0.18 0.76 0.0 -0.3 -1.0 0.53
36015 BRD-K98684188 PC3 10 uM 24 h 0.0 0.0 0.0 0.31 1.08 0.66
36390 BRD-K98684188 PHH 10 uM 24 h 0.0 0.0 0.0 0.21 0.73 0.03
36691 BRD-K98684188 SKB 10 uM 24 h 0.0 0.0 0.0 0.41 1.44 2.21
36902 BRD-K98684188 VCAP 10 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).