CMap Candidate Details

Structure:
CMap ID: C03368
Pert ID: BRD-K02992638
Compound Name: lamivudine
Targets: --
MoA: --
SMILES: Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1
InchiKey: JTEGQNOMFQHVDC-NKWVEPMBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
20239 BRD-K02992638 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21021 BRD-K02992638 MCF??7.00 10 uM 6 h 0.25 1.04 0.14 0.0 0.0 0.0
25319 BRD-K02992638 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51912 BRD-K02992638 PC3 10 uM 6 h -0.25 -1.05 0.24 0.0 0.0 0.0
122915 BRD-K02992638 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122951 BRD-K02992638 HELA 0.37 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
122989 BRD-K02992638 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123040 BRD-K02992638 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
123130 BRD-K02992638 MDAMB231 1.11 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
123202 BRD-K02992638 THP1 10 uM 24 h 0.32 1.34 0.89 0.0 0.0 0.0
131219 BRD-K02992638 A375 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131258 BRD-K02992638 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131290 BRD-K02992638 HA1E 0.74 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
131377 BRD-K02992638 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131413 BRD-K02992638 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
131510 BRD-K02992638 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).