CMap Candidate Details

Structure:
CMap ID: C33682
Pert ID: BRD-K98763141
Compound Name: niflumic-acid
Targets: CLCNKA; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: OC(=O)c1cccnc1Nc1cccc(c1)C(F)(F)F
InchiKey: JZFPYUNJRRFVQU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49921 BRD-K98763141 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50084 BRD-K98763141 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50271 BRD-K98763141 HA1E 10 uM 6 h 0.21 0.86 0.01 0.0 0.0 0.0
50619 BRD-K98763141 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51083 BRD-K98763141 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51251 BRD-K98763141 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51537 BRD-K98763141 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91262 BRD-K98763141 HUH7 12 uM 72 h 0.0 0.0 0.0 -0.25 -0.83 0.16
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).