CMap Candidate Details

Structure:
CMap ID: C33689
Pert ID: BRD-K98795921
Compound Name: SB-2343
Targets: MTOR; PIK3CA; PIK3CB; PIK3CD; PIK3CG
MoA: MTOR inhibitor; PI3K inhibitor
SMILES: CC(C)n1c(C)nc2c(nc(nc12)N1CCOCC1)-c1cnc(N)nc1
InchiKey: QYBGBLQCOOISAR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
87282 BRD-K98795921 BJAB 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87336 BRD-K98795921 HBL1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87384 BRD-K98795921 K562 10 uM 24 h 0.0 0.0 0.0 0.21 0.74 0.04
87433 BRD-K98795921 KMS34 0.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87481 BRD-K98795921 MINO 2.5 uM 24 h 0.0 0.0 0.0 -0.19 -0.62 0.0
87536 BRD-K98795921 NALM6 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87586 BRD-K98795921 OCILY10 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87638 BRD-K98795921 OCILY19 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
87686 BRD-K98795921 OCILY3 2.5 uM 24 h 0.0 0.0 0.0 -0.17 -0.59 0.0
87737 BRD-K98795921 SKMEL5 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87811 BRD-K98795921 THP1 10 uM 6 h 0.0 0.0 0.0 0.18 0.64 0.0
87841 BRD-K98795921 TMD8 10 uM 3 h 0.0 0.0 0.0 -0.22 -0.76 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).