CMap Candidate Details

Structure:
CMap ID: C03372
Pert ID: BRD-K03015355
Compound Name: forskolin
Targets: ADCY2
MoA: Adenylyl cyclase activator
SMILES: CN1CCN(CCCC(=O)O[C@H]2[C@@H](O)[C@H]3C(C)(C)CC[C@H](O)[C@]3(C)[C@@]4(O)C(=O)C[C@@](C)(O[C@]24C)C=C)CC1
InchiKey: PAYHDZDDAHVPDU-ZQVYKFDISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4183 BRD-K03015355 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4340 BRD-K03015355 HCC515 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.15
4635 BRD-K03015355 PC3 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
4876 BRD-K03015355 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44280 BRD-K03015355 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44658 BRD-K03015355 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44816 BRD-K03015355 ASC 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
45131 BRD-K03015355 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45400 BRD-K03015355 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45760 BRD-K03015355 MCF??7.00 10 uM 6 h -0.2 -0.82 0.0 -0.28 -0.96 0.42
46250 BRD-K03015355 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46566 BRD-K03015355 SKB 10 uM 24 h -0.23 -0.95 0.08 -0.31 -1.05 0.68
99976 BRD-K03015355 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.77
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).