CMap Candidate Details

Structure:
CMap ID: C33731
Pert ID: BRD-K98948170
Compound Name: BRD-K98948170
Targets: KEAP1
MoA: Kelch-like ECH-associated protein ligand
SMILES: OC(=O)[C@H]1CCCC[C@H]1C(=O)N1CCc2ccccc2[C@H]1CN1C(=O)c2ccccc2C1=O
InchiKey: LNENLABLFGGAFF-BHIFYINESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
117228 BRD-K98948170 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119114 BRD-K98948170 JURKAT 3.33 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
119194 BRD-K98948170 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119220 BRD-K98948170 A549 10 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
119250 BRD-K98948170 HA1E 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.36
119281 BRD-K98948170 HCC515 10 uM 24 h 0.27 1.15 0.32 0.0 0.0 0.0
119309 BRD-K98948170 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119359 BRD-K98948170 MCF??7.00 3.33 uM 24 h 0.26 1.07 0.19 -0.29 -0.99 0.5
119382 BRD-K98948170 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).