CMap Candidate Details

Structure:
CMap ID: C33757
Pert ID: BRD-K99023089
Compound Name: AZD-5363
Targets: --
MoA: --
SMILES: NC1(CCN(CC1)c1ncnc2[nH]ccc12)C(=O)N[C@@H](CCO)c1ccc(Cl)cc1
InchiKey: JDUBGYFRJFOXQC-KRWDZBQOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1227 BRD-K99023089 A549 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
1305 BRD-K99023089 MCF??7.00 10 uM 6 h 0.24 0.99 0.1 0.0 0.0 0.0
1393 BRD-K99023089 U2OS 10 uM 6 h -0.23 -0.97 0.11 0.0 0.0 0.0
127754 BRD-K99023089 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127832 BRD-K99023089 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127882 BRD-K99023089 HEK293 1.11 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
127905 BRD-K99023089 HT29 10 uM 24 h 0.0 0.0 0.0 -0.46 -1.53 15.35
127956 BRD-K99023089 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128007 BRD-K99023089 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.7
128056 BRD-K99023089 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128089 BRD-K99023089 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.73
135583 BRD-K99023089 HELA 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
135674 BRD-K99023089 JURKAT 2.22 uM 24 h -0.21 -0.89 0.03 -0.34 -1.14 1.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).