CMap Candidate Details

Structure:
CMap ID: C33781
Pert ID: BRD-K99107520
Compound Name: felbamate
Targets: GRIN3A; GRIN2A; GRIN2B
MoA: Glutamate receptor antagonist
SMILES: NC(=O)OCC(COC(N)=O)c1ccccc1
InchiKey: WKGXYQFOCVYPAC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3422 BRD-K99107520 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3917 BRD-K99107520 VCAP 10 uM 24 h 0.2 0.84 0.0 -0.24 -0.82 0.15
24707 BRD-K99107520 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42504 BRD-K99107520 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42813 BRD-K99107520 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43678 BRD-K99107520 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43978 BRD-K99107520 PHH 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
44226 BRD-K99107520 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121782 BRD-K99107520 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.36
121833 BRD-K99107520 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121863 BRD-K99107520 YAPC 0.37 uM 24 h -0.3 -1.23 0.64 -0.41 -1.37 2.02
129746 BRD-K99107520 A375 0.01 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
129779 BRD-K99107520 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
129810 BRD-K99107520 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129864 BRD-K99107520 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129908 BRD-K99107520 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129936 BRD-K99107520 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129987 BRD-K99107520 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.34
130021 BRD-K99107520 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130094 BRD-K99107520 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).