CMap Candidate Details

Structure:
CMap ID: C33866
Pert ID: BRD-K99411983
Compound Name: lumicolchicine
Targets: --
MoA: --
SMILES: COC1=C[C@H]2[C@H](C3=C2c4c(OC)c(OC)c(OC)cc4CC[C@@H]3NC(=O)C)C1=O
InchiKey: VKPVZFOUXUQJMW-FHSNZYRGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5380 BRD-K99411983 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5811 BRD-K99411983 HCC515 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.72
6226 BRD-K99411983 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6608 BRD-K99411983 VCAP 10 uM 6 h 0.24 1.01 0.12 -0.33 -1.11 0.9
41861 BRD-K99411983 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42161 BRD-K99411983 A549 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.58
42506 BRD-K99411983 ASC 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
42815 BRD-K99411983 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43100 BRD-K99411983 HT29 10 uM 6 h -0.25 -1.04 0.21 -0.3 -1.01 0.56
43249 BRD-K99411983 MCF??7.00 10 uM 24 h 0.23 0.95 0.06 -0.31 -1.06 0.72
43680 BRD-K99411983 NPC 10 uM 24 h -0.29 -1.22 0.62 0.0 0.0 0.0
44228 BRD-K99411983 SKB 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).