CMap Candidate Details

Structure:
CMap ID: C03387
Pert ID: BRD-K03067624
Compound Name: emetine
Targets: RPS2
MoA: Protein synthesis inhibitor
SMILES: CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc12
InchiKey: AUVVAXYIELKVAI-CKBKHPSWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1155 BRD-K03067624 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1275 BRD-K03067624 MCF??7.00 0.12 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.12
13747 BRD-K03067624 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14587 BRD-K03067624 HA1E 10 uM 6 h 0.26 1.08 0.22 0.0 0.0 0.0
14737 BRD-K03067624 HCC515 10 uM 6 h 0.3 1.25 0.53 -0.48 -1.63 15.65
15192 BRD-K03067624 HT29 10 uM 6 h 0.33 1.39 1.02 -0.38 -1.28 1.44
15579 BRD-K03067624 PC3 10 uM 24 h 0.28 1.16 0.35 -0.49 -1.67 15.65
53430 BRD-K03067624 HEPG2 10 uM 6 h 0.24 1.0 0.11 -0.34 -1.15 1.06
53559 BRD-K03067624 HUH7 10 uM 6 h 0.25 1.05 0.16 -0.43 -1.46 15.35
53638 BRD-K03067624 PHH 2.5 uM 24 h 0.25 1.03 0.13 -0.45 -1.52 15.35
99977 BRD-K03067624 U2OS 3.33 uM 6 h 0.21 0.88 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).