CMap Candidate Details

Structure:
CMap ID: C33934
Pert ID: BRD-K99604664
Compound Name: tanaproget
Targets: PGR
MoA: Progesterone receptor agonist
SMILES: Cn1c(ccc1-c1ccc2NC(=S)OC(C)(C)c2c1)C#N
InchiKey: PYVFWTPEBMRKSR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128121 BRD-K99604664 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128192 BRD-K99604664 HT29 10 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
128243 BRD-K99604664 MCF10A 1.11 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
128322 BRD-K99604664 MDAMB231 0.04 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
135785 BRD-K99604664 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135827 BRD-K99604664 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135866 BRD-K99604664 HEK293 2.22 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
135917 BRD-K99604664 HELA 2.22 uM 24 h 0.18 0.75 0.0 -0.36 -1.2 1.21
136007 BRD-K99604664 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136037 BRD-K99604664 MCF??7.00 2.22 uM 24 h -0.19 -0.77 0.0 -0.23 -0.79 0.11
136068 BRD-K99604664 PC3 2.22 uM 24 h 0.19 0.8 0.0 -0.25 -0.85 0.19
136100 BRD-K99604664 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136153 BRD-K99604664 YAPC 2.22 uM 24 h -0.3 -1.26 0.73 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).