CMap Candidate Details
Structure:
| CMap ID: | C33980 |
| Pert ID: | BRD-K99741577 |
| Compound Name: | SANT-1 |
| Targets: | SHH; SMO |
| MoA: | Smoothened receptor antagonist |
| SMILES: | Cc1nn(c(C)c1C=NN1CCN(Cc2ccccc2)CC1)-c1ccccc1 |
| InchiKey: | FOORCIAZMIWALX-JJIBRWJFSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95483 | BRD-K99741577 | A549 | 10 uM | 24 h | -0.23 | -0.94 | 0.08 | -0.33 | -1.11 | 0.92 |
| 95571 | BRD-K99741577 | MCF??7.00 | 10 uM | 48 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 95615 | BRD-K99741577 | U2OS | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96597 | BRD-K99741577 | A375 | 10 uM | 24 h | 0.24 | 1.02 | 0.13 | -0.29 | -0.99 | 0.5 |
| 96670 | BRD-K99741577 | PC3 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.17 |