CMap Candidate Details

Structure:
CMap ID: C03400
Pert ID: BRD-K03109492
Compound Name: NSC-663284
Targets: CDC25A; CDC25B
MoA: CDC inhibitor
SMILES: ClC1=C(NCCN2CCOCC2)C(=O)c2ncccc2C1=O
InchiKey: BMKPVDQDJQWBPD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5174 BRD-K03109492 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5421 BRD-K03109492 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5569 BRD-K03109492 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6000 BRD-K03109492 HT29 10 uM 6 h 0.26 1.07 0.19 0.0 0.0 0.0
6081 BRD-K03109492 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6253 BRD-K03109492 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6319 BRD-K03109492 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37361 BRD-K03109492 A549 10 uM 6 h -0.18 -0.75 0.0 -0.48 -1.61 15.65
37580 BRD-K03109492 ASC 10 uM 24 h 0.31 1.28 0.6 -0.39 -1.32 1.71
53431 BRD-K03109492 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53560 BRD-K03109492 HUH7 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96004 BRD-K03109492 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99979 BRD-K03109492 U2OS 10 uM 6 h -0.26 -1.08 0.28 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).