CMap Candidate Details

Structure:
CMap ID: C34006
Pert ID: BRD-K99818283
Compound Name: PIK-90
Targets: --
MoA: --
SMILES: COc1ccc2C3=NCCN3C(=Nc2c1OC)NC(=O)c4cccnc4
InchiKey: ZJAVHOMVDCMAMF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9014 BRD-K99818283 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9258 BRD-K99818283 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9558 BRD-K99818283 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10101 BRD-K99818283 HA1E 10 uM 6 h -0.25 -1.04 0.21 0.0 0.0 0.0
10320 BRD-K99818283 HCC515 10 uM 6 h -0.19 -0.8 0.0 0.0 0.0 0.0
10641 BRD-K99818283 HCT116 10 uM 6 h 0.0 0.0 0.0 0.22 0.76 0.05
10889 BRD-K99818283 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
11047 BRD-K99818283 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11311 BRD-K99818283 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
11629 BRD-K99818283 NCIH2073 10 uM 6 h -0.18 -0.73 0.0 0.0 0.0 0.0
12182 BRD-K99818283 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12421 BRD-K99818283 NOMO1 10 uM 6 h 0.0 0.0 0.0 -0.17 -0.57 0.0
12522 BRD-K99818283 PC3 10 uM 24 h -0.21 -0.86 0.01 0.28 0.99 0.39
12915 BRD-K99818283 SW480 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.72
13046 BRD-K99818283 THP1 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.38
13407 BRD-K99818283 U937 10 uM 6 h 0.0 0.0 0.0 0.31 1.08 0.67
13715 BRD-K99818283 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).