CMap Candidate Details

Structure:
CMap ID: C34077
Pert ID: BRD-M16762496
Compound Name: PIK-75
Targets: PIK3CA
MoA: PI3K inhibitor; DNA protein kinase inhibitor
SMILES: CN(N=Cc1cnc2ccc(Br)cn12)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
InchiKey: QTHCAAFKVUWAFI-DJKKODMXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33711 BRD-M16762496 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33952 BRD-M16762496 A549 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.51
34227 BRD-M16762496 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34459 BRD-M16762496 HA1E 10 uM 6 h 0.0 0.0 0.0 0.41 1.46 2.23
34731 BRD-M16762496 HCC515 10 uM 6 h 0.0 0.0 0.0 0.36 1.26 1.29
35006 BRD-M16762496 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35239 BRD-M16762496 HT29 10 uM 6 h 0.0 0.0 0.0 0.25 0.9 0.22
35362 BRD-M16762496 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35649 BRD-M16762496 NEU 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
35881 BRD-M16762496 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36120 BRD-M16762496 PC3 10 uM 6 h 0.0 0.0 0.0 0.32 1.13 0.84
36699 BRD-M16762496 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36909 BRD-M16762496 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).