CMap Candidate Details

Structure:
CMap ID: C34106
Pert ID: BRD-M30523314
Compound Name: vinorelbine
Targets: TUBB
MoA: Tubulin inhibitor
SMILES: CCC1=C[C@@H]2C[N@](C1)Cc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC
InchiKey: GBABOYUKABKIAF-JEEMQKELSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33865 BRD-M30523314 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34228 BRD-M30523314 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
34460 BRD-M30523314 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34732 BRD-M30523314 HCC515 10 uM 6 h -0.23 -0.98 0.11 0.0 0.0 0.0
35007 BRD-M30523314 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35240 BRD-M30523314 HT29 10 uM 6 h 0.17 0.7 0.0 0.0 0.0 0.0
35363 BRD-M30523314 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35650 BRD-M30523314 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35882 BRD-M30523314 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36019 BRD-M30523314 PC3 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.75
36399 BRD-M30523314 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36700 BRD-M30523314 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36910 BRD-M30523314 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).