CMap Candidate Details
Structure:
| CMap ID: | C34144 |
| Pert ID: | BRD-M47793593 |
| Compound Name: | picrotoxin |
| Targets: | GABRA1; GABRR1; GLRA2; GLRA3 |
| MoA: | GABA receptor antagonist |
| SMILES: | CC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C.CC(C)(O)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@@]53C |
| InchiKey: | VJKUPQSHOVKBCO-AHMKVGDJSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24516 | BRD-M47793593 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.03 | 0.62 |
| 24708 | BRD-M47793593 | A549 | 10 uM | 6 h | -0.2 | -0.82 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24976 | BRD-M47793593 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.27 | -0.92 | 0.33 |
| 25060 | BRD-M47793593 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.93 | 0.26 |
| 25210 | BRD-M47793593 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.34 | -1.14 | 1.01 |
| 25461 | BRD-M47793593 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |