CMap Candidate Details

Structure:
CMap ID: C34169
Pert ID: BRD-M62162320
Compound Name: rilmenidine
Targets: NISCH; ADRA2A
MoA: Adrenergic receptor agonist; Imidazoline receptor agonist
SMILES: C1CC1C(NC2=NCCO2)C3CC3
InchiKey: CQXADFVORZEARL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3084 BRD-M62162320 HA1E 10 uM 6 h 0.23 0.97 0.08 -0.24 -0.81 0.13
3424 BRD-M62162320 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3579 BRD-M62162320 PC3 10 uM 24 h 0.0 0.0 0.0 0.28 1.01 0.44
3919 BRD-M62162320 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44469 BRD-M62162320 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44633 BRD-M62162320 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45063 BRD-M62162320 ASC 10 uM 24 h -0.23 -0.97 0.11 -0.3 -1.01 0.56
45344 BRD-M62162320 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45604 BRD-M62162320 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45731 BRD-M62162320 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46172 BRD-M62162320 NPC 10 uM 24 h -0.26 -1.09 0.32 -0.25 -0.83 0.16
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).