CMap Candidate Details

Structure:
CMap ID: C34186
Pert ID: BRD-M72442222
Compound Name: vicriviroc
Targets: CCR5
MoA: CCK receptor antagonist
SMILES: COC[C@H](N1CCN(C[C@@H]1C)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(cc1)C(F)(F)F
InchiKey: CNPVJJQCETWNEU-CYFREDJKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33716 BRD-M72442222 A375 10 uM 6 h 0.0 0.0 0.0 -0.45 -1.5 15.35
33866 BRD-M72442222 A549 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.43 15.35
34230 BRD-M72442222 ASC 10 uM 24 h -0.23 -0.98 0.12 -0.32 -1.08 0.81
34462 BRD-M72442222 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34734 BRD-M72442222 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.14 1.05
35009 BRD-M72442222 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.21 0.75 0.04
35242 BRD-M72442222 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35365 BRD-M72442222 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35652 BRD-M72442222 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35884 BRD-M72442222 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36021 BRD-M72442222 PC3 10 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
36401 BRD-M72442222 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36702 BRD-M72442222 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.15
37022 BRD-M72442222 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).